Ontology highlight
ABSTRACT:
SUBMITTER: Lepri SR
PROVIDER: S-EPMC3560877 | biostudies-literature | 2013 Mar
REPOSITORIES: biostudies-literature
Lepri Sandra Regina SR Luiz Rodrigo Cabral RC Zanelatto Leonardo Campos LC da Silva Patrícia Benites Gonçalves PB Sartori Daniele D Ribeiro Lucia Regina LR Mantovani Mario Sergio MS
Cytotechnology 20120630 2
Isoflavones are phenolic compounds widely distributed in plants and found in a high percentage in soybeans. They have important biological properties and are regarded as potential chemopreventive agents. The aim of this study was to verify the preventive effect of two soy isoflavones (genistein and daidzein) by a micronucleus assay, analysis of GST activity, and real-time RT-PCR analysis of GSTa2 gene expression. Mutagens of direct (doxorubicin) and indirect (2-aminoanthracene) DNA damage were u ...[more]