Ontology highlight
ABSTRACT:
SUBMITTER: Yoshimoto N
PROVIDER: S-EPMC3561619 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Yoshimoto Nobuo N Kida Akiko A Jie Xu X Kurokawa Masaya M Iijima Masumi M Niimi Tomoaki T Maturana Andrés D AD Nikaido Itoshi I Ueda Hiroki R HR Tatematsu Kenji K Tanizawa Katsuyuki K Kondo Akihiko A Fujii Ikuo I Kuroda Shun'ichi S
Scientific reports 20130201
When establishing the most appropriate cells from the huge numbers of a cell library for practical use of cells in regenerative medicine and production of various biopharmaceuticals, cell heterogeneity often found in an isogenic cell population limits the refinement of clonal cell culture. Here, we demonstrated high-throughput screening of the most suitable cells in a cell library by an automated undisruptive single-cell analysis and isolation system, followed by expansion of isolated single cel ...[more]