Ontology highlight
ABSTRACT:
SUBMITTER: Al-Halabi L
PROVIDER: S-EPMC3564879 | biostudies-literature | 2013 Jan-Feb
REPOSITORIES: biostudies-literature
Al-Halabi Laila L Balck Anne A Michalzik Monika M Fröde David D Büttgenbach Stephanus S Hust Michael M Schirrmann Thomas T Dübel Stefan S
mAbs 20121206 1
C-reactive protein (CRP) is a serum marker highly upregulated in inflammation after bacterial infection. Robust, reliable and quick quantification of CRP would be a substitute for erythrocyte sedimentation rate (ESR) with superior diagnostic value. Quartz crystal microbalance (QCM) based sensors coated with specific antibodies and integrated into lab-on-chip systems are in development for rapid point of care quantification. In this study, we isolated three CRP specific single chain (sc)Fv antibo ...[more]