Ontology highlight
ABSTRACT:
SUBMITTER: Lehrnbecher T
PROVIDER: S-EPMC3566394 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Lehrnbecher Thomas T Schmidt Stanislaw S Tramsen Lars L Klingebiel Thomas T
Frontiers in oncology 20130207
Despite the availability of new antifungal compounds, invasive fungal infection remains a significant cause of morbidity and mortality in children and adults undergoing allogeneic hematopoietic stem cell transplantation (HSCT). Allogeneic HSCT recipients suffer from a long lasting defect of different arms of the immune system, which increases the risk for and deteriorates the prognosis of invasive fungal infections. In turn, advances in understanding these immune deficits have resulted in promis ...[more]