Ontology highlight
ABSTRACT:
SUBMITTER: Reddy MS
PROVIDER: S-EPMC3566765 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Reddy Maddi Sridhar MS Thirupathi Nuligonda N Haribabu Madala M
Beilstein journal of organic chemistry 20130128
Cu-catalyzed A(3) coupling of ethoxyacetylene, pyrrolidine and salicylaldehydes led to a concomitant cycloisomerization followed by hydrolysis of the resultant vinyl ether to afford coumarins in a cascade process. The reaction proceeded through exclusive 6-endo-dig cyclization and is compatible with halo and keto groups giving coumarins in good to moderate yields. ...[more]