Ontology highlight
ABSTRACT:
SUBMITTER: Plummer EM
PROVIDER: S-EPMC3567616 | biostudies-literature | 2012 Jun
REPOSITORIES: biostudies-literature
Plummer Emily M EM Thomas Diane D Destito Giuseppe G Shriver Leah P LP Manchester Marianne M
Nanomedicine (London, England) 20120306 6
<h4>Aims</h4>Detection of atherosclerosis has generally been limited to the late stages of development, after cardiovascular symptoms present or a clinical event occurs. One possibility for early detection is the use of functionalized nanoparticles. The aim of this study was the early imaging of atherosclerosis using nanoparticles with a natural affinity for inflammatory cells in the lesion.<h4>Materials & methods</h4>We investigated uptake of cowpea mosaic virus by macrophages and foam cells in ...[more]