Ontology highlight
ABSTRACT:
SUBMITTER: Low CG
PROVIDER: S-EPMC3568134 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Low Christopher G CG Luk Iris S U IS Lin Dong D Fazli Ladan L Yang Kuo K Xu Yong Y Gleave Martin M Gout Peter W PW Wang Yuzhuo Y
PloS one 20130208 2
<h4>Background</h4>BIRC6 is a member of the Inhibitors of Apoptosis Protein (IAP) family which is thought to protect a variety of cancer cells from apoptosis. The main objective of the present study was to investigate whether BIRC6 plays a role in prostate cancer and could be useful as a novel therapeutic target.<h4>Methods</h4>BIRC6 expression in cell lines was assessed using Western blot analysis and in clinical samples using immunohistochemistry of tissue microarrays. The biological significa ...[more]