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A window into the invisible wound of war: functional neuroimaging of REM sleep in returning combat veterans with PTSD.


ABSTRACT: Relative regional cerebral metabolic rate of glucose in rapid eye movement (REM) sleep and wakefulness was explored in combat veterans with and without posttraumatic stress disorder PTSD, using positron emission tomography. Hypermetabolism in brain regions involved in arousal regulation, fear responses, and reward processing persist during REM sleep in combat veterans with PTSD.

SUBMITTER: Germain A 

PROVIDER: S-EPMC3570584 | biostudies-literature | 2013 Feb

REPOSITORIES: biostudies-literature

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A window into the invisible wound of war: functional neuroimaging of REM sleep in returning combat veterans with PTSD.

Germain Anne A   James Jeffrey J   Insana Salvatore S   Herringa Ryan J RJ   Mammen Oommen O   Price Julie J   Nofzinger Eric E  

Psychiatry research 20121111 2


Relative regional cerebral metabolic rate of glucose in rapid eye movement (REM) sleep and wakefulness was explored in combat veterans with and without posttraumatic stress disorder PTSD, using positron emission tomography. Hypermetabolism in brain regions involved in arousal regulation, fear responses, and reward processing persist during REM sleep in combat veterans with PTSD. ...[more]

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