Ontology highlight
ABSTRACT:
SUBMITTER: Chang B
PROVIDER: S-EPMC3572115 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
PloS one 20130213 2
To account for the functional non-equivalence among a set of genes within a biological pathway when performing gene set analysis, we introduce GOGANPA, a network-based gene set analysis method, which up-weights genes with functions relevant to the gene set of interest. The genes are weighted according to its degree within a genome-scale functional network constructed using the functional annotations available from the gene ontology database. By benchmarking GOGANPA using a well-studied P53 data ...[more]