Cognitive effects of intramuscular ketamine and oral triazolam in healthy volunteers.
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ABSTRACT:
SUBMITTER: Carter LP
PROVIDER: S-EPMC3572303 | biostudies-literature | 2013 Mar
REPOSITORIES: biostudies-literature
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Cognitive effects of intramuscular ketamine and oral triazolam in healthy volunteers.
Carter Lawrence P LP Kleykamp Bethea A BA Griffiths Roland R RR Mintzer Miriam Z MZ
Psychopharmacology 20121025 1
<h4>Rationale</h4>Several studies have documented impairments in memory processes as a result of ketamine administration; however, few studies have compared the profile of cognitive effects of ketamine to other drugs.<h4>Objectives</h4>The aim of this study was to compare the cognitive effects of ketamine with those of triazolam in healthy volunteers.<h4>Methods</h4>Doses of ketamine (0.2, 0.4 mg/kg intramuscular (i.m.)), triazolam (0.2, 0.4 mg/70 kg p.o.), and double-dummy placebos were adminis ...[more]
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