Ontology highlight
ABSTRACT:
SUBMITTER: Kramer MF
PROVIDER: S-EPMC3572766 | biostudies-literature | 2011 Sep
REPOSITORIES: biostudies-literature
Virology 20110723 2
Several herpes simplex virus 1 microRNAs are encoded within or near the latency associated transcript (LAT) locus, and are expressed abundantly during latency. Some of these microRNAs can repress the expression of important viral proteins and are hypothesized to play important roles in establishing and/or maintaining latent infections. We found that in lytically infected cells and in acutely infected mouse ganglia, expression of LAT-encoded microRNAs was weak and unaffected by a deletion that in ...[more]