Ontology highlight
ABSTRACT:
SUBMITTER: Chetram MA
PROVIDER: S-EPMC3578043 | biostudies-literature | 2013 Apr
REPOSITORIES: biostudies-literature
Chetram Mahandranauth A MA Bethea Danaya A DA Odero-Marah Valerie A VA Don-Salu-Hewage Ayesha S AS Jones Kia J KJ Hinton Cimona V CV
Molecular and cellular biochemistry 20130112 1-2
Reactive oxygen species (ROS) play a central role in oxidative stress, which leads to the onset of diseases, such as cancer. Furthermore, ROS contributes to the delicate balance between tumor cell survival and death. However, the mechanisms by which tumor cells decide to elicit survival or death signals during oxidative stress are not completely understood. We have previously reported that ROS enhanced tumorigenic functions in prostate cancer cells, such as transendothelial migration and invasio ...[more]