Ontology highlight
ABSTRACT:
SUBMITTER: Chan KW
PROVIDER: S-EPMC3578129 | biostudies-literature | 2013 Mar
REPOSITORIES: biostudies-literature
Chan Kannie W Y KW Liu Guanshu G Song Xiaolei X Kim Heechul H Yu Tao T Arifin Dian R DR Gilad Assaf A AA Hanes Justin J Walczak Piotr P van Zijl Peter C M PC Bulte Jeff W M JW McMahon Michael T MT
Nature materials 20130127 3
Biocompatible nanomaterials and hydrogels have become an important tool for improving cell-based therapies by promoting cell survival and protecting cell transplants from immune rejection. Although their potential benefit has been widely evaluated, at present it is not possible to determine, in vivo, if and how long cells remain viable following their administration without the use of a reporter gene. Here, we report a pH-nanosensor-based magnetic resonance imaging (MRI) technique that can monit ...[more]