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Pd(II)-catalyzed enantioselective C-H activation/C-O bond formation: synthesis of chiral benzofuranones.

ABSTRACT: Pd(II)-catalyzed enantioselective C-H activation of phenylacetic acids followed by an intramolecular C-O bond formation afforded chiral benzofuranones. This reaction provides the first example of enantioselecctive C-H functionalizations through Pd(II)/Pd(IV) redox catalysis.

SUBMITTER: Cheng XF

PROVIDER: S-EPMC3578945 | biostudies-literature | 2013 Jan

REPOSITORIES: biostudies-literature

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Pd(II)-catalyzed enantioselective C-H activation/C-O bond formation: synthesis of chiral benzofuranones.

Cheng Xiu-Fen XF Li Yan Y Su Yi-Ming YM Yin Feng F Wang Jian-Yong JY Sheng Jie J Vora Harit U HU Wang Xi-Sheng XS Yu Jin-Quan JQ

Journal of the American Chemical Society 20130114 4

Pd(II)-catalyzed enantioselective C-H activation of phenylacetic acids followed by an intramolecular C-O bond formation afforded chiral benzofuranones. This reaction provides the first example of enantioselecctive C-H functionalizations through Pd(II)/Pd(IV) redox catalysis. ...[more]

PMID: 23305171

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