Ontology highlight
ABSTRACT:
SUBMITTER: Juhling F
PROVIDER: S-EPMC3579883 | biostudies-literature | 2012 Sep
REPOSITORIES: biostudies-literature
Jühling Frank F Pütz Joern J Florentz Catherine C Stadler Peter F PF
RNA biology 20120901 9
The mitochondrial genome of metazoan animal typically encodes 22 tRNAs. Nematode mt-tRNAs normally lack the T-stem and instead feature a replacement loop. In the class Enoplea, putative mt-tRNAs that are even further reduced have been predicted to lack both the T- and the D-arm. Here we investigate these tRNA candidates in detail. Three lines of computational evidence support that they are indeed minimal functional mt-tRNAs: (1) the high level of conservation of both sequence and secondary struc ...[more]