Ontology highlight
ABSTRACT:
SUBMITTER: Mantia-Smaldone GM
PROVIDER: S-EPMC3579897 | biostudies-literature | 2012 Sep
REPOSITORIES: biostudies-literature
Mantia-Smaldone Gina M GM Corr Bradley B Chu Christina S CS
Human vaccines & immunotherapeutics 20120821 9
Ovarian cancer is the most deadly gynecologic malignancy, with more than 15,000 deaths anticipated in 2012. While approximately 80% of patients will respond to frontline chemotherapy, more than 60% of patients will experience disease recurrence and only 44% will be alive at 5 y. Host anti-tumor immune responses are associated with a significant improvement in overall survival for women with ovarian cancer. By bolstering these responses, it may therefore be possible to significantly influence the ...[more]