Ontology highlight
ABSTRACT:
SUBMITTER: Lorenz UJ
PROVIDER: S-EPMC3581949 | biostudies-literature | 2013 Feb
REPOSITORIES: biostudies-literature
Lorenz Ulrich J UJ Zewail Ahmed H AH
Proceedings of the National Academy of Sciences of the United States of America 20130204 8
We present a technique for in situ visualization of the biomechanics of DNA structural networks using 4D electron microscopy. Vibrational oscillations of the DNA structure are excited mechanically through a short burst of substrate vibrations triggered by a laser pulse. Subsequently, the motion is probed with electron pulses to observe the impulse response of the specimen in space and time. From the frequency and amplitude of the observed oscillations, we determine the normal modes and eigenfreq ...[more]