Ontology highlight
ABSTRACT:
SUBMITTER: Xi S
PROVIDER: S-EPMC3582115 | biostudies-literature | 2013 Mar
REPOSITORIES: biostudies-literature
Xi Sichuan S Xu Hong H Shan Jigui J Tao Yongguang Y Hong Julie A JA Inchauste Suzanne S Zhang Mary M Kunst Tricia F TF Mercedes Leandro L Schrump David S DS
The Journal of clinical investigation 20130215 3
MicroRNAs are critical mediators of stem cell pluripotency, differentiation, and malignancy. Limited information exists regarding microRNA alterations that facilitate initiation and progression of human lung cancers. In this study, array techniques were used to evaluate microRNA expression in normal human respiratory epithelia and lung cancer cells cultured in the presence or absence of cigarette smoke condensate (CSC). Under relevant exposure conditions, CSC significantly repressed miR-487b. Su ...[more]