Ontology highlight
ABSTRACT:
SUBMITTER: Jokerst JV
PROVIDER: S-EPMC3582222 | biostudies-literature | 2012 Jul
REPOSITORIES: biostudies-literature
Jokerst Jesse V JV Thangaraj Mridhula M Kempen Paul J PJ Sinclair Robert R Gambhir Sanjiv S SS
ACS nano 20120620 7
Improved imaging modalities are critically needed for optimizing stem cell therapy. Techniques with real-time content to guide and quantitate cell implantation are especially important in applications such as musculoskeletal regenerative medicine. Here, we report the use of silica-coated gold nanorods as a contrast agent for photoacoustic imaging and quantitation of mesenchymal stem cells in rodent muscle tissue. The silica coating increased the uptake of gold into the cell more than 5-fold, yet ...[more]