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3-Hy-droxy-1-(4-meth-oxy-benz-yl)piperidin-2-one.

ABSTRACT: The title compound, C13H17NO3, adopts a conformation in which the aromatic ring and the mean plane of the piperidine ring are almost perpendicular to each other [dihedral angle = 79.25?(6)°]. The presence of the carbonyl group alters the conformation of the piperidine ring from a chair to a twisted half-chair conformation. In the crystal, pairs of strong O-H?O hydrogen bonds link the mol-ecules into inversion dimers. Weak C-H?O inter-actions extend the hydrogen-bonding network into three dimensions.

SUBMITTER: Pienaar DP

PROVIDER: S-EPMC3588348 | biostudies-literature | 2013 Jan

REPOSITORIES: biostudies-literature

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3-Hy-droxy-1-(4-meth-oxy-benz-yl)piperidin-2-one.

Pienaar Daniel P DP Khorasani Sanaz S de Koning Charles B CB Michael Joseph P JP

Acta crystallographica. Section E, Structure reports online 20121208 Pt 1

The title compound, C13H17NO3, adopts a conformation in which the aromatic ring and the mean plane of the piperidine ring are almost perpendicular to each other [dihedral angle = 79.25 (6)°]. The presence of the carbonyl group alters the conformation of the piperidine ring from a chair to a twisted half-chair conformation. In the crystal, pairs of strong O-H⋯O hydrogen bonds link the mol-ecules into inversion dimers. Weak C-H⋯O inter-actions extend the hydrogen-bonding network into three dimensi ...[more]

PMID: 23476435

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