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(1'S,4'S)-5-(2,5-Dimethyl-phen-yl)-4'-meth-oxy-6-oxa-3-aza-spiro-[bicyclo-[3.1.0]hexane-2,1'-cyclo-hexa-n]-4-one.

ABSTRACT: In the title compound, C18H23NO3, the cyclo-hexane ring has a chair conformation. The oxirane plane (OCC) makes a dihedral angle of 76.15?(13)° with that of the pyrrolidine ring to which it is fused. The mean plane of the cyclo-hexane ring and the benzene ring are almost normal to the pyrrolidine ring, with dihedral angles of 88.47?(8) and 77.85?(8)°, respectively. In the crystal, mol-ecules are linked via pairs of N-H?O hydrogen bonds, forming inversion dimers. These dimers are linked via pairs of C-H?O hydrogen bonds, forming chains along the a-axis direction.

SUBMITTER: He XR

PROVIDER: S-EPMC3588543 | biostudies-literature | 2013 Mar

REPOSITORIES: biostudies-literature

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(1'S,4'S)-5-(2,5-Dimethyl-phen-yl)-4'-meth-oxy-6-oxa-3-aza-spiro-[bicyclo-[3.1.0]hexane-2,1'-cyclo-hexa-n]-4-one.

He Xing-Rui XR Xu Bing-Rong BR Cheng Jing-Li JL Zhao Jin-Hao JH

Acta crystallographica. Section E, Structure reports online 20130228 Pt 3

In the title compound, C18H23NO3, the cyclo-hexane ring has a chair conformation. The oxirane plane (OCC) makes a dihedral angle of 76.15 (13)° with that of the pyrrolidine ring to which it is fused. The mean plane of the cyclo-hexane ring and the benzene ring are almost normal to the pyrrolidine ring, with dihedral angles of 88.47 (8) and 77.85 (8)°, respectively. In the crystal, mol-ecules are linked via pairs of N-H⋯O hydrogen bonds, forming inversion dimers. These dimers are linked via pairs ...[more]

PMID: 23476621

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