SpoIVA and SipL are Clostridium difficile spore morphogenetic proteins.
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ABSTRACT:
SUBMITTER: Putnam EE
PROVIDER: S-EPMC3592010 | biostudies-literature | 2013 Mar
REPOSITORIES: biostudies-literature
Publications
SpoIVA and SipL are Clostridium difficile spore morphogenetic proteins.
Putnam Emily E EE Nock Adam M AM Lawley Trevor D TD Shen Aimee A
Journal of bacteriology 20130104 6
Clostridium difficile is a major nosocomial pathogen whose infections are difficult to treat because of their frequent recurrence. The spores of C. difficile are responsible for these clinical features, as they resist common disinfectants and antibiotic treatment. Although spores are the major transmissive form of C. difficile, little is known about their composition or morphogenesis. Spore morphogenesis has been well characterized for Bacillus sp., but Bacillus sp. spore coat proteins are poorl ...[more]
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