Ontology highlight
ABSTRACT:
SUBMITTER: Lund TC
PROVIDER: S-EPMC3592821 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Lund Troy C TC Kobs Amanda J AJ Kramer Ashley A Nyquist Mick M Kuroki Marcos T MT Osborn John J Lidke Diane S DS Low-Nam Shalini T ST Blazar Bruce R BR Tolar Jakub J
PloS one 20130308 3
The ability of cells to detect changes in the microenvironment is important in cell signaling and responsiveness to environmental fluctuations. Our interest is in understanding how human bone marrow stromal-derived cells (MSC) and their relatives, vascular smooth muscle cells (VSMC), interact with their environment through novel receptors. We found, through a proteomics screen, that MSC express the bitter taste receptor, TAS2R46, a protein more typically localized to the taste bud. Expression wa ...[more]