Ontology highlight
ABSTRACT:
SUBMITTER: Rajagopal N
PROVIDER: S-EPMC3597546 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Rajagopal Nisha N Xie Wei W Li Yan Y Wagner Uli U Wang Wei W Stamatoyannopoulos John J Ernst Jason J Kellis Manolis M Ren Bing B
PLoS computational biology 20130314 3
Transcriptional enhancers play critical roles in regulation of gene expression, but their identification in the eukaryotic genome has been challenging. Recently, it was shown that enhancers in the mammalian genome are associated with characteristic histone modification patterns, which have been increasingly exploited for enhancer identification. However, only a limited number of cell types or chromatin marks have previously been investigated for this purpose, leaving the question unanswered whet ...[more]