Flaviviruses: braking the entering.
Ontology highlight
ABSTRACT:
SUBMITTER: Pierson TC
PROVIDER: S-EPMC3601797 | biostudies-literature | 2013 Feb
REPOSITORIES: biostudies-literature
Publications
Flaviviruses: braking the entering.
Pierson Theodore C TC Kielian Margaret M
Current opinion in virology 20130124 1
Flaviviruses are small spherical virus particles covered by a dense icosahedral array of envelope (E) proteins that mediate virus attachment to cells and the fusion of viral and cellular membranes. Our understanding of the mechanism by which flavivirus E proteins orchestrate entry into cells has been advanced by studies of E structure and arrangement on the virion at different steps of the virus entry/membrane fusion process. When combined with an increasingly clear (albeit still incomplete) vie ...[more]
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