Ontology highlight
ABSTRACT:
SUBMITTER: Jeong J
PROVIDER: S-EPMC3602797 | biostudies-literature | 2013 Apr-Jun
REPOSITORIES: biostudies-literature
Jeong Jeeyon J Eide David J DJ
Molecular aspects of medicine 20130401 2-3
Zinc is a trace element nutrient that is essential for life. This mineral serves as a cofactor for enzymes that are involved in critical biochemical processes and it plays many structural roles as well. At the cellular level, zinc is tightly regulated and disruption of zinc homeostasis results in serious physiological or pathological issues. Despite the high demand for zinc in cells, free or labile zinc must be kept at very low levels. In humans, two major zinc transporter families, the SLC30 (Z ...[more]