Ontology highlight
ABSTRACT:
SUBMITTER: Zhang Z
PROVIDER: S-EPMC3606897 | biostudies-literature | 2013 Jan
REPOSITORIES: biostudies-literature
Zhang Zhonghai Z Yin Lichen L Tu Chunlai C Song Ziyuan Z Zhang Yanfeng Y Xu Yunxiang Y Tong Rong R Zhou Qin Q Ren Jie J Cheng Jianjun J
ACS macro letters 20121224 1
Monomethoxy poly(ethylene glycol)-<i>b</i>-poly(Tyr(alkynyl)-OCA), a biodegradable amphiphilic block copolymer, was synthesized by means of ring-opening polymerization of 5-(4-(prop-2-yn-1-yloxy)benzyl)-1,3-dioxolane-2,4-dione (Tyr(alkynyl)-OCA) and used to prepare core cross-linked polyester micelles via click chemistry. Core cross-linking not only improved the structural stability of the micelles but also allowed controlled release of cargo molecules in response to the reducing reagent. This n ...[more]