Ontology highlight
ABSTRACT:
SUBMITTER: Dollendorf C
PROVIDER: S-EPMC3778402 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Dollendorf Christian C Hetzer Martin M Ritter Helmut H
Beilstein journal of organic chemistry 20130813
A redox-responsive polycationic system was synthesized via copolymerization of N,N-diethylacrylamide (DEAAm) and 2-(dimethylamino)ethyl methacrylate (DMAEMA). N,N'-bis(4-chlorobutanoyl)cystamine was used as disulfide-containing cross-linker to form networks by the quaternization of tertiary amine groups. The insoluble cationic hydrogels become soluble by reduction of disulfide to mercaptanes by use of dithiothreitol (DTT), tris(2-carboxyethyl)phosphine (TCEP) or cysteamine, respectively. The sol ...[more]