Ontology highlight
ABSTRACT:
SUBMITTER: Jian L
PROVIDER: S-EPMC3608465 | biostudies-literature | 2013 Mar
REPOSITORIES: biostudies-literature
Jian Ling L Niu Xinnan X Xia Zhonghang Z Samir Parimal P Sumanasekera Chiranthani C Mu Zheng Z Jennings Jennifer L JL Hoek Kristen L KL Allos Tara T Howard Leigh M LM Edwards Kathryn M KM Weil P Anthony PA Link Andrew J AJ
Journal of proteome research 20130212 3
Liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) has revolutionized the proteomics analysis of complexes, cells, and tissues. In a typical proteomic analysis, the tandem mass spectra from a LC-MS/MS experiment are assigned to a peptide by a search engine that compares the experimental MS/MS peptide data to theoretical peptide sequences in a protein database. The peptide spectra matches are then used to infer a list of identified proteins in the original sample. However, the ...[more]