Ontology highlight
ABSTRACT:
SUBMITTER: Tang Q
PROVIDER: S-EPMC3610570 | biostudies-literature | 2011 Nov
REPOSITORIES: biostudies-literature
Cancer research 20110922 22
Nuclear receptors comprise a superfamily of ligand-activated transcription factors that play important roles in both physiology and diseases including cancer. The technologies of chromatin immunoprecipitation followed by array hybridization (ChIP-chip) or massively parallel sequencing (ChIP-seq) has been used to map, at an unprecedented rate, the in vivo genome-wide binding (cistrome) of nuclear receptors in both normal and cancer cells. We developed a curated database of 88 nuclear receptor cis ...[more]