Ontology highlight
ABSTRACT:
SUBMITTER: Bareke E
PROVIDER: S-EPMC3622648 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Bareke Eric E Saillour Virginie V Spinella Jean-François JF Vidal Ramon R Healy Jasmine J Sinnett Daniel D Csűrös Miklós M
BMC bioinformatics 20130410
The joint sequencing of related genomes has become an important means to discover rare variants. Normal-tumor genome pairs are routinely sequenced together to find somatic mutations and their associations with different cancers. Parental and sibling genomes reveal de novo germline mutations and inheritance patterns related to Mendelian diseases.Acute lymphoblastic leukemia (ALL) is the most common paediatric cancer and the leading cause of cancer-related death among children. With the aim of unc ...[more]