Ontology highlight
ABSTRACT:
SUBMITTER: van der Harst P
PROVIDER: S-EPMC3623669 | biostudies-literature | 2012 Dec
REPOSITORIES: biostudies-literature
Nature 20121205 7429
Anaemia is a chief determinant of global ill health, contributing to cognitive impairment, growth retardation and impaired physical capacity. To understand further the genetic factors influencing red blood cells, we carried out a genome-wide association study of haemoglobin concentration and related parameters in up to 135,367 individuals. Here we identify 75 independent genetic loci associated with one or more red blood cell phenotypes at P < 10(-8), which together explain 4-9% of the phenotypi ...[more]