Ontology highlight
ABSTRACT:
SUBMITTER: Kato A
PROVIDER: S-EPMC3628816 | biostudies-literature | 2013 Apr
REPOSITORIES: biostudies-literature
Kato Atsushi A Hulse Kathryn E KE Tan Bruce K BK Schleimer Robert P RP
The Journal of allergy and clinical immunology 20130401 4
Adaptive humoral immune responses in the airways are mediated by B cells and plasma cells that express highly evolved and specific receptors and produce immunoglobulins of most isotypes. In some cases, such as autoimmune diseases or inflammatory diseases caused by excessive exposure to foreign antigens, these same immune cells can cause disease by virtue of overly vigorous responses. This review discusses the generation, differentiation, signaling, activation, and recruitment pathways of B cells ...[more]