Ontology highlight
ABSTRACT:
SUBMITTER: Morinaga H
PROVIDER: S-EPMC3632121 | biostudies-literature | 2013 Apr
REPOSITORIES: biostudies-literature
Morinaga Hironobu H Takenaka Tomohiro T Hashiya Fumitaka F Kizaki Seiichiro S Hashiya Kaori K Bando Toshikazu T Sugiyama Hiroshi H
Nucleic acids research 20130225 8
Electron transfer in DNA has been intensively studied to elucidate its biological roles and for applications in bottom-up DNA nanotechnology. Recently, mechanisms of electron transfer to DNA have been investigated; however, most of the systems designed are intramolecular. Here, we synthesized pyrene-conjugated pyrrole-imidazole polyamides (PPIs) to achieve sequence-specific electron injection into DNA in an intermolecular fashion. Electron injection from PPIs into DNA was detected using 5-bromou ...[more]