Ontology highlight
ABSTRACT:
SUBMITTER: Lee JS
PROVIDER: S-EPMC3632878 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Lee Jae-Seung JS Parasoglou Prodromos P Xia Ding D Jerschow Alexej A Regatte Ravinder R RR
Scientific reports 20130101
The development of chemical exchange saturation transfer (CEST) has led to the establishment of new contrast mechanisms in magnetic resonance imaging, which serve as enablers for advanced molecular imaging strategies. Macromolecules in tissues and organs often give rise to broad and asymmetric exchange effects, called magnetization transfer (MT) effects, which can mask the CEST contrast of interest. We show here that the saturation of these macromolecular pools simultaneously at two distinct fre ...[more]