Naturally acquired Mycobacterium tuberculosis complex in laboratory pig-tailed macaques.
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ABSTRACT:
SUBMITTER: Engel GA
PROVIDER: S-EPMC3636427 | biostudies-literature | 2012 Oct
REPOSITORIES: biostudies-literature
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Naturally acquired Mycobacterium tuberculosis complex in laboratory pig-tailed macaques.
Engel Gregory A GA Wilbur Alicia K AK Westmark Andrew A Horn Dara D Johnson Jordan J Jones-Engel Lisa L
Emerging microbes & infections 20121010 10
Here we present a case series from a primate research facility. The index case, a 4-year-old pig-tailed macaque (Macaca nemestrina) experimentally infected with chimeric simian-human immunodeficiency virus (SHIVSF162 P4), developed weight loss and was euthanized. Based on necropsy results the animal was diagnosed with opportunistic atypical mycobacteriosis associated with simian AIDS (SAIDS). Subsequently, tissues from the index animal, as well as tissues and oral mucosal swabs from six SHIV-inf ...[more]
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