Ontology highlight
ABSTRACT:
SUBMITTER: Fritsch EB
PROVIDER: S-EPMC3640625 | biostudies-literature | 2013 Feb
REPOSITORIES: biostudies-literature
Fritsch Erika B EB Connon Richard E RE Werner Inge I Davies Rebecca E RE Beggel Sebastian S Feng Wei W Pessah Isaac N IN
Environmental science & technology 20130128 4
Triclosan (TCS), a high volume chemical widely used in consumer products, is a known aquatic contaminant found in fish inhabiting polluted watersheds. Mammalian studies have recently demonstrated that TCS disrupts signaling between the ryanodine receptor (RyR) and the dihydropyridine receptor (DHPR), two proteins essential for excitation-contraction (EC) coupling in striated muscle. We investigated the swimming behavior and expression of EC coupling proteins in larval fathead minnows (Pimephales ...[more]