Dataset Information

Acute electrocardiographic changes during smoking: an observational study.

ABSTRACT:

Objective

To study the temporal relationship of smoking with electrophysiological changes.

Design

Prospective observational study.

Setting

Tertiary cardiac center.

Participants

Male smokers with atypical chest pain were screened with a treadmill exercise test (TMT). A total of 31 such patients aged 49.8±10.5 years, in whom TMT was either negative or mildly positive were included. Heart rate variability (HRV) parameters of smokers were compared to those of 15 healthy non-smoking participants.

Interventions

All patients underwent a 24 h Holter monitoring to assess ECG changes during smoking periods.

Results

Heart rate increased acutely during smoking. Mean heart rate increased from 83.8±13.7 bpm 10 min before smoking, to 90.5±16.4 bpm during smoking, (p<0.0001) and returned to baseline after 30 min. Smoking was also associated with increased ectopic beats (mean of 5.3/h prior to smoking to 9.8/h during smoking to 11.3/h during the hour after smoking; p<0.001). Three patients (9.7%) had significant ST-T changes after smoking. HRV index significantly decreased in smokers (15.2±5.3) as compared to non-smoking controls participants (19.4±3.6; p=0.02), but the other spectral HRV parameters were comparable.

Conclusions

Heart rate and ectopic beats increase acutely following smoking. Ischaemic ST-T changes were also detected during smoking. Spectral parameters of HRV analysis of smokers remained in normal limits, but more importantly geometrical parameter-HRV index-showed significant abnormality.

SUBMITTER: Ramakrishnan S

PROVIDER: S-EPMC3641479 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Acute electrocardiographic changes during smoking: an observational study.

Ramakrishnan Sivasubramanian S Bhatt Kinjal K Dubey Akhilesh K AK Roy Ambuj A Singh Sandeep S Naik Nitish N Seth Sandeep S Bhargava Balram B

BMJ open 20130405 4

<h4>Objective</h4>To study the temporal relationship of smoking with electrophysiological changes.<h4>Design</h4>Prospective observational study.<h4>Setting</h4>Tertiary cardiac center.<h4>Participants</h4>Male smokers with atypical chest pain were screened with a treadmill exercise test (TMT). A total of 31 such patients aged 49.8±10.5 years, in whom TMT was either negative or mildly positive were included. Heart rate variability (HRV) parameters of smokers were compared to those of 15 healthy ...[more]

PMID: 23562816

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Dataset Information

Acute electrocardiographic changes during smoking: an observational study.

Objective

Design

Setting

Participants

Interventions

Results

Conclusions

Publications

Acute electrocardiographic changes during smoking: an observational study.

Similar Datasets

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