Ontology highlight
ABSTRACT:
SUBMITTER: Wu X
PROVIDER: S-EPMC3641593 | biostudies-literature | 2013 May
REPOSITORIES: biostudies-literature
Cell research 20130212 5
microRNAs (miRNAs) play important roles in the regulation of gene expression. In Arabidopsis, mature miRNAs are processed from primary miRNA transcripts (pri-miRNAs) by nuclear HYL1/SE/DCL1 complexes that form Dicing bodies (D-bodies). Here we report that an RNA-binding protein MOS2 binds to pri-miRNAs and is involved in efficient processing of pri-miRNAs. MOS2 does not interact with HYL1, SE, and DCL1 and is not localized in D-bodies. Interestingly, in the absence of MOS2, the recruitment of pr ...[more]