Ontology highlight
ABSTRACT:
SUBMITTER: Li R
PROVIDER: S-EPMC3646462 | biostudies-literature | 2013 Jun
REPOSITORIES: biostudies-literature
Li Rongsong R Navab Mohamad M Pakbin Payam P Ning Zhi Z Navab Kaveh K Hough Greg G Morgan Todd E TE Finch Caleb E CE Araujo Jesus A JA Fogelman Alan M AM Sioutas Constantinos C Hsiai Tzung T
Journal of lipid research 20130406 6
Exposure to ambient particulate matter (PM) is a risk factor for cardiovascular diseases. The redox-active ultrafine particles (UFPs) promote vascular oxidative stress and inflammatory responses. We hypothesized that UFPs modulated lipid metabolism and anti-oxidant capacity of high density lipoprotein (HDL) with an implication in atherosclerotic lesion size. Fat-fed low density lipoprotein receptor-null (LDLR⁻/⁻ mice were exposed to filtered air (FA) or UFPs for 10 weeks with or without administ ...[more]