Ontology highlight
ABSTRACT:
SUBMITTER: Klengel T
PROVIDER: S-EPMC3646525 | biostudies-literature | 2005 Nov
REPOSITORIES: biostudies-literature
Klengel Torsten T Liang Wei-Jun WJ Chaloupka James J Ruoff Claudia C Schröppel Klaus K Naglik Julian R JR Eckert Sabine E SE Mogensen Estelle Gewiss EG Haynes Ken K Tuite Mick F MF Levin Lonny R LR Buck Jochen J Mühlschlegel Fritz A FA
Current biology : CB 20051101 22
The ascomycete Candida albicans is the most common fungal pathogen in immunocompromised patients . Its ability to change morphology, from yeast to filamentous forms, in response to host environmental cues is important for virulence . Filamentation is mediated by second messengers such as cyclic adenosine 3',5'-monophosphate (cAMP) synthesized by adenylyl cyclase . The distantly related basidiomycete Cryptococcus neoformans is an encapsulated yeast that predominantly infects the central nervous s ...[more]