Ontology highlight
ABSTRACT:
SUBMITTER: Negron LM
PROVIDER: S-EPMC3646530 | biostudies-literature | 2013 Mar
REPOSITORIES: biostudies-literature
Journal of the American Chemical Society 20130227 10
We describe precise supramolecules that enable the evaluation of the effective hydrophobicity of amphiphilic or "patchy" nanoglobular systems. These supramolecules exhibit the lower critical solution temperature phenomenon, which provides a quantitative measure of their effective hydrophobicity. Specifically, two isomeric 8-aryl-2'-deoxyguanosine derivatives with a transposed pair of methylene groups self-assemble into hexadecameric nanoglobular supramolecular G-quadruplexes (SGQs) that show lar ...[more]