An aquatic host-guest complex between a supramolecular G-quadruplex and the anticancer drug doxorubicin.
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ABSTRACT:
SUBMITTER: Rivera JM
PROVIDER: S-EPMC3646657 | biostudies-literature | 2012 Oct
REPOSITORIES: biostudies-literature
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An aquatic host-guest complex between a supramolecular G-quadruplex and the anticancer drug doxorubicin.
Rivera José M JM Martín-Hidalgo Mariana M Rivera-Ríos Jean C JC
Organic & biomolecular chemistry 20121001 37
We describe the synthesis of a fluorescent deoxyguanosine derivative that co-assembles (in water) with an unlabeled analogue into a heteromeric supramolecular G-quadruplex, which forms a host-guest complex with doxorubicin as evidenced by FRET experiments. ...[more]
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