Size compatibility and concentration dependent supramolecular host-guest interactions at interfaces.

ABSTRACT: The quantification of supramolecular host-guest interactions is important for finely modulating supramolecular systems. Previously, most host-guest interactions quantified using force spectroscopic techniques have been reported in force units. However, accurately evaluating the adhesion energies of host-guest pairs remains challenging. Herein, using a surface forces apparatus, we directly quantify the interaction energies between cyclodextrin (CD)-modified surfaces and ditopic adamantane (DAd) molecules in water as a function of the DAd concentration and the CD cavity size. The adhesion energy of the β-CD-DAd complex drastically increased with increasing DAd concentration and reached saturation. Moreover, the molecular adhesion energy of a single host-guest inclusion complex was evaluated

SUBMITTER: Park J 

PROVIDER: S-EPMC8748952 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature