Ontology highlight
ABSTRACT:
SUBMITTER: Hahne F
PROVIDER: S-EPMC3648208 | biostudies-literature | 2010 Feb
REPOSITORIES: biostudies-literature
Hahne Florian F Khodabakhshi Alireza Hadj AH Bashashati Ali A Wong Chao-Jen CJ Gascoyne Randy D RD Weng Andrew P AP Seyfert-Margolis Vicky V Bourcier Katarzyna K Asare Adam A Lumley Thomas T Gentleman Robert R Brinkman Ryan R RR
Cytometry. Part A : the journal of the International Society for Analytical Cytology 20100201 2
Between-sample variation in high-throughput flow cytometry data poses a significant challenge for analysis of large-scale data sets, such as those derived from multicenter clinical trials. It is often hard to match biologically relevant cell populations across samples because of technical variation in sample acquisition and instrumentation differences. Thus, normalization of data is a critical step before analysis, particularly in large-scale data sets from clinical trials, where group-specific ...[more]