Ontology highlight
ABSTRACT:
SUBMITTER: Shuang B
PROVIDER: S-EPMC3648847 | biostudies-literature | 2013 Jan
REPOSITORIES: biostudies-literature
Langmuir : the ACS journal of surfaces and colloids 20121220 1
Two maximum likelihood estimation (MLE) methods were developed for optimizing the analysis of single-molecule trajectories that include phenomena such as experimental noise, photoblinking, photobleaching, and translation or rotation out of the collection plane. In particular, short, single-molecule trajectories with photoblinking were studied, and our method was compared to existing analytical techniques applied to simulated data. The optimal method for various experimental cases was established ...[more]