Ontology highlight
ABSTRACT:
SUBMITTER: Asadi-Khiavi M
PROVIDER: S-EPMC3648953 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Asadi-Khiavi Masoud M Hamzeiy Hossein H Khani Sajjad S Nakhlband Ailar A Barar Jaleh J
BioImpacts : BI 20110731 2
<h4>Introduction</h4>Gap junctions play an important role in the cell proliferation in mammalian cells as well as carcinogenesis. However, there are controversial issues about their role in cancer pathogenesis. This study was designed to evaluate genotoxicity and cytotoxicity of Carbenoxolone (CBX) as a prototype of inter-cellular gap junction blocker in MCF7 and BT20 human breast cancer cells.<h4>Methods</h4>The MCF7and BT20 human breast cancer cell lines were cultivated, and treated at designa ...[more]