Ontology highlight
ABSTRACT:
SUBMITTER: Donaldson ZR
PROVIDER: S-EPMC3652904 | biostudies-literature | 2013 Jun
REPOSITORIES: biostudies-literature
Donaldson Zoe R ZR Nautiyal Katherine M KM Ahmari Susanne E SE Hen René R
Current opinion in neurobiology 20130204 3
Serotonin (5-hydroxytryptamine; 5-HT) is an ancient signaling molecule that has a conserved role in modulating mood and behavior. Integral to its pleiotropic actions is the existence of multiple receptors, expressed in distinct but often overlapping patterns within the brain and the periphery. The existence of ∼14 mammalian receptor subtypes, many of which possess similar pharmacological profiles, has made assigning functional roles for these receptors challenging. This challenge has been furthe ...[more]