Ontology highlight
ABSTRACT:
SUBMITTER: Hughes JF
PROVIDER: S-EPMC3653425 | biostudies-literature | 2010 Jan
REPOSITORIES: biostudies-literature
Nature 20100113 7280
The human Y chromosome began to evolve from an autosome hundreds of millions of years ago, acquiring a sex-determining function and undergoing a series of inversions that suppressed crossing over with the X chromosome. Little is known about the recent evolution of the Y chromosome because only the human Y chromosome has been fully sequenced. Prevailing theories hold that Y chromosomes evolve by gene loss, the pace of which slows over time, eventually leading to a paucity of genes, and stasis. Th ...[more]