Chromatin-tethered MAPKs.
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ABSTRACT:
SUBMITTER: Klein AM
PROVIDER: S-EPMC3654648 | biostudies-literature | 2013 Apr
REPOSITORIES: biostudies-literature
Publications
Chromatin-tethered MAPKs.
Klein Aileen M AM Zaganjor Elma E Cobb Melanie H MH
Current opinion in cell biology 20130220 2
Mitogen-activated protein kinases (MAPKs) are a family of protein kinases that are essential nodes in many cellular regulatory circuits including those that take place on DNA. Most members of the four MAPK subgroups that exist in canonical three kinase cascades-extracellular signal-regulated kinases 1 and 2 (ERK1/2), ERK5, c-Jun N-terminal kinases (JNK1-3), and p38 (α, β, γ, and δ) families-have been shown to perform regulatory functions on chromatin. This review offers a brief update on the var ...[more]
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